CORRELATION OF DAYS OF FEVER AND THE NUMBER OF TROMBOSITES ON SECONDARY AND PRIMARY DENGUE HEMORRHAGIC FEVER INFECTION

Abstract

Dengue Hemorrhagic Fever (DHF) is caused by four variants of the Dengue Hemorrhagic Fever (DHF) virus of the Flaviviridae family (DENV-1, DENV-2, DENV-3, and DENV-4). These four variants are indistinguishable clinically. The occurrence of platelet deterioration is sometimes not accompanied by positive IgG and IgM DHF results, nor can they be negative. In DHF sufferers, platelet decline will decrease steadily during the 3rd to 6th day and will increase on the 7th day. This research is retrospective analytical with cross sectional approach. The samples were 15 patients of Secondary DHF and 15 Primary DHF who have fulfilled the inclusion criteria. The day of fever when the patient came to the Poli Internal Medicine Dr. Soetomo Hospital is known from the patient's history, while the results of IgG and IgM DHF examination and platelet count are performed in KLINIKA Surabaya laboratory. The result of this study used correlation parametric test (Pearson's test), to know the relationship of day of fever and platelet count in Secondary and Primary DHF patients with α = 0,05. Result of day of fever with p = .659 (p>0.05). The result of thrombocyte count with Pearson's test (p= .042) (p<0.05) showed a correlation of platelet count between Secondary and Primary DHF patients. It was concluded that there was a significant correlation the number of platelets between Secondary and Primary DHF.