Sosialisasi Vaksinasi Covid-19 dan Pemeriksaan IgG Kuantitatif Pre dan Pasca Vaksinasi Kepada Mahasiswa Magang di RSI Jemursari Surabaya

Authors

  • Bastiana Bastiana Universitas Nahdlatul Ulama Surabaya, Indonesia
  • Diyan Wahyu K Universitas Nahdlatul Ulama Surabaya, Indonesia
  • Notrisia Rachmayanti Universitas Nahdlatul Ulama Surabaya, Indonesia
  • Maharani Pertiwi Koentjoro Universitas Nahdlatul Ulama Surabaya, Indonesia
  • Prima Ardiansah Surya Universitas Nahdlatul Ulama Surabaya, Indonesia

Keywords:

sosialisasi, vaksinasi, IG kuantitatif, Covid-19

Abstract

Latar Belakang Masih banyak mahasiswa magang di lingkungan RSI Jemursari Surabaya yang belum paham betul perihal vaksinasi Covid-19, sehingga perlu diadakan sosialisasi untuk mendapatkan pemahaman yang lebih baik dan meningkatkan keikutsertaan vaksinasi. Penilaian efektivitas vaksin yang penting untuk dievaluasi, mendorong penyelenggara untuk melakukan pemeriksaan kadar antibodi yang terbentuk pada mahasiswa setelah menerima vaksinasi Covid-19. Kadar antibodi Ig G kuantitatif diharapkan akan meningkat secara signifikan setelah pemberian vaksinasi Covid-19. Metode Sosialisasi vaksinasi Covid-19 dilakukan secara daring berupa presentasi dan tanya jawab. Pemeriksaan kadar antibodi IgG kuantitatif dilakukan di Laboratorium RSI Jemursari menggunakan metode CLIA (Chemiluminescence Immunoassay) sebelum vaksinasi dan 28 hari sesudah vaksinasi. Data diolah secara
statistik untuk mengetahui apakah ada perbedaan bermakna sebelum dan sesudah vaksinasi (p<0,05). Hasil dan Pembahasan Sosialisasi mengenai vaksin dilakukan untuk menambah wawasan mengenai vaksinasi Covid-19 dan meningkatkan kesadaran ikut serta vaksinasi sebagai upaya memberikan herd immunity untuk melindungi diri dan orang disekitarnya. Sedangkan pemeriksaan antibodi IgG kuantitatif dilakukan untuk mengamati respon pembentukan antibodi pada mahasiswa penerima vaksin sebagai
tanda telah terbentuknya kekebalan terhadap Covid-19. Sosialisasi vaksinasi Covid-19 telah dilakukan pada pada 35 mahasiswa secara daring menggunakan metode presentasi dan tanya jawab. Dari 35 orang mahasiswa yang mengikuti sosialisasi, semua mengikuti vaksinasi. Sebanyak 25 orang bersedia mengikuti pemeriksaan antibodi IgG kuantitatif (pre dan pasca vaksinasi). Kadar antibodi rerata pre vaksinasi sebesar 35,33 AU/L, sedangkan sesudah vaksinasi (hari ke 28 pasca vaksinasi) sebesar 424,64 AU/L. Berdasarkan
uji statistik hasil pemeriksaan antibodi IgG kuantitatif menunjukkan ada perbedaan bermakna kadar antibodi IgG terhadap virus Covid-19 sebelum dan sesudah vaksinasi (p< 0,05). Kesimpulan Sosialisasi vaksinasi Covid-19 berdampak positif. Hasil penelitian menunjukkan peningkatan signifikan antibodi IgG terhadap Covid-19 sesudah vaksinasi. Perlu dilakukan pemeriksaan kadar antibodi IgG serial untuk mengetahui berapa lama antibodi ini dapat bertahan.

References

Aleanizy, F. A., Alqahtani, F. Y. (2021). Awareness and knowledge of COVID-19 infection control precautions and waste management among healthcare workers. Medicine (Baltimore). 100(21). e26102. https://dx.doi.org/10.1097%2FMD.0000000000026102

Bandyopadhyay, S., Baticulon, R., Kadhum, M., Alser, M., Ojuka, D. K., Bedereddin, Y., Kamath, A., Parepali, S. A., Brown, G., Iharchane, S., Gandino, S., Markovic-Obiago, Z., Scoot, S., Manirambona, E., Machhada, A., Aggarwal, A., Benazaiza, L., Ibrahim, M., Kim, D., Tol, I., Taylor, E. H., Knighton A., Bbaale, D., Jasim, D., Alghoul, H., Reddy, H., Abuelgasim, H., Saini, K., Sigler, A., Abuelgasim, L., Moran-Romero, M., Kumarendran, M., Jamie, N. A., Ali, O., Sudarshan, R., Dean, R., Kissyova, R., Kelzang, S., Roche, S., Ahsan, T., Mohamed, Y., Dube, A. M., Gwini, G. P., Gwokyala, R., Brown, R., Papon, M. R. K. K., Li, Z., Ruzats, S. S., Charuvila, S., Peter, N., Khalidy, K., Moyo, N., Alser, O., Solano, A., Robles-Perez, E., Tariq, A., Gaddah, M., Kolovos, S., Muchemwa, F., Saleh, A., Gosman, A., Pinedo-Villanueva, R. P., Jani, A., Khundar, R. (2020).

Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review. BMJ Public Health Emergency Colection. 5(12). e003097. https://dx.doi.org/10.1136%2Fbmjgh-2020-003097

Bhagavathula, A. S., Aldhaleei, W. A., Rahmani, J., Mahabadi, M. A., Bandari, D. K. (2020). Knowledge and perceptions of COVID-19 among healthcare workers: Cross-sectinal study. JMIR Public Health Surveill. 6(2). e191160. https://dx.doi.org/10.2196%2F19160

Chopra, S., Ranjan, P., Singh, S., Kumar, S., Arora, M., Hasan, M., Kasiraj, R., Suryansh, Kaur, D., Vikram, N., Malhotra, A., Kumari, A., Klanidhi, K., Baitha, U. (2020). Impact of COVID-19 on lifestyle-related-behaviors-a cross-sectional audit of responses from nine hundred and ninetyfive participants from India. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(6), 2021–2030. https://dx.doi.org/10.1016%2Fj.dsx.2020.09.034

Erdem, H., Lucey, D. (2021). Healthcare worker infections and deaths due to COVID-19: A survey from 37 nations and a call for WHO to post national data on their website. International Journal of Infectious Disease. 102: 239-241. https://dx.doi.org/10.1016%2Fj.ijid.2020.10.064

Hou, H., Wang, T., Zhang, B., Luo, Y., Mao, L., Wang, F., Wu, S., Sun, Z. (2020). Detection of IgM and IgG antibodies in patients with coronavirus disease 2019. Clinical & Translational Immunology. 9(5). e1136. https://dx.doi.org/10.1002%2Fcti2.1136

Iwasaki, A., Omer, S. B. (2020). Why and How Vaccines Work. Elsevier Public Health Emergency Collection. 183(2). 290-295. https://dx.doi.org/10.1016%2Fj.cell.2020.09.040

Koltai, J., Raifman, J., Bor, J., McKee, M., Stuckler, D. (2021). Does COVID-19 vaccination improve mental health? A difference-in-difference analysis of the understanding coronavirus in America study. medRxiv. https://doi.org/10.1101/2021.07.19.21260782

Kourlaba, G., Kourkouni, E., Maistreli, S., Tsopela, C., Molocha, N., Triantafyllou, C., Koniordou, M., Kopsidas, L., Chorianopoulou, E., Moroudi-Manta, S., Flippou, D., Zaoutis, T. E. (2021). Willingness of Greesk general population to get a COVID-19 vaccine. Global Health Research and Policy. https://dx.doi.org/10.1186%2Fs41256-021-00188-1

Kumari, A., Ranjan, P., Chopra, S., Kaur, D., Kaur, T., Upadhyay, A. D., Isaac, J. A., Kasiraj, R., Prakash, B., Kmar, P., Dwivedi, S. N., Vikram, N. K. (2021). Knowledge, barriers and facilitators regarding COVID-19 vaccine and vaccination among the general population: A cross-sectional survey from one thousand two hundred and forty-nine participants. Elsevier Public Health Emergency Collection. 15(3). 987-992. https://dx.doi.org/10.1016%2Fj.dsx.2021.04.015

Mazumder, A., Kalanidhi, K. B., Sarkar, S., Ranjan, P., Sahu, A., Kaur, T., Kaur, D., Bhattacharya, A., Suna, S. P., Prakash, B., Deb, K.S., Wig, N. (2021). Psycho-social and behavioural impact of COVID-19 on young adults: Qualitative research comprising focused group discussion and in-depth interviews. Elsevier Public Health Emergency Collection, 14(1), 309-312. https://dx.doi.org/10.1016%2Fj.dsx.2020.12.039

Mbachu, C. N. P., Azubuike, C. M., Mbachu, I. I., Ndukwu, C. I., Ezeuko, A. Y., Udigwe, I. B., Nnamani, C. P., Umeh, U. M., Ezeagwuna, D. A., Onah, S. K., Eze, H. O., Okereke U. C., Orji-Ifeanyi, E. N. (2020). COVID-19 infection: Knowledge, attitude, practices, and impact among healthcare workers in a South-Eastern Nigerian state. Journal Infection of Developmental Countries. 14(9). 943-952. https://doi.org/10.3855/jidc.13248

Mohamed, N.A., Solehan, H. M., Rani, M.D.M., Ithnin, M., Isahak, C.I.C. (2021). Knowledge, acceptance and perception on COVID-19 vaccine among Malaysians: A web-based survey. PLoS ONE, 16(8), Article e0256110. https://dx.doi.org/10.1371%2Fjournal.pone.0256110

Olliaro, P., Torreele, E., Vailant, M. (2021). COVID-19 vaccine efficacy and effectiveness-the elephant (not) in the room. Elsevier Public Health Emergency Collection. 2(7). e273-e280. https://dx.doi.org/10.1016%2FS2666-5247(21)00069-0

Tanis, J., Vancutsem, E., Perard, D., Weets, I., Bjerke, M., Schiettecatte, J., Geyter, D. D. (2021). Evaluation of four laboratory-based SARS CoV-2 IgG antibody immunoassays. Elsevier Public Health Emergency Collection. 100(1). 115313. https://dx.doi.org/10.1016%2Fj.diagmicrobio.2021.115313

Tretyn, A., Szczepanek, J., Skorupa, M., Jarkiewicz-Tretyn, J., Sandomierz, D., Dejewska, J., Ciechanowska, K., Jarkiewicz-Tretyn, A., Koper, W., Palgan, K. (2021). Differences in the concentration of anti-SARS-CoV-2 IgG antibodies post-COVID-19 recovery of post-vaccination. Cells. 10(8). 1952. https://dx.doi.org/10.3390%2Fcells10081952

Wakefield, M., Loken, B., Hornik, R. (2010). Use of mass media campaingns to change health behavior. Lancet. 376(9748). 1261-1271.

https://dx.doi.org/10.1016%2FS0140-6736(10)60809-4

Zurac, S., Nichita, L., Mateescu, B., Mogodici, C., Bastian, A., Popp, C., Cioplea, M., Socoliuc, C., Constantin, C., Neagu, M. (2021). COVID-19 vaccination and IgG and IgA antibody dynamics in healthcare workers. Molecular Medicine Reports. 24(2). 578. https://dx.doi.org/10.3892%2Fmmr.2021.12217

Downloads

Published

2022-01-25