@article{Seftiana_Wulan_Wulandari_2020, title={The Effect Of Long Exposure To Pesticide Organophosphate On Cholinesterase Enzyme Activity In The Blood}, volume={1}, url={https://conferences.unusa.ac.id/index.php/SIHC19/article/view/517}, abstractNote={<p>The high use of pesticides increases the health risks faced, both for pesticide operators and the community<br>at large. Synthetic group pesticides that are widely used by farmers in Indonesia are organophosphate groups. These<br>organophosphate compounds are unstable in the environment but are more toxic to vertebrate animals because they<br>can affect the nervous system by inhibiting cholinesterase enzyme activity in the body. The purpose of this study was<br>to analyze the effect of exposure to organophosphate pesticides on the activity of cholinesterase enzymes in the<br>blood of factory workers in fertilizer and pesticide industries. This study used an observational analytic study design<br>with cross sectional design. The sample of this study was the pesticide production operator which amounted to 15<br>respondents who had different lengths of work taking blood for the examination of cholinesterase enzymes using the<br>method of kinetic photometric test method recommended by the German Society of Clinical Chemistry (DGKC).<br>Data analysis techniques with One Way Anova test. The results of the examination of the respondents cholinesterase<br>levels showed a value between 5981 U/L - 12006 U/L which was categorized as mild and normal poisoning. The<br>One Way Anova test results obtained the length of work of <10 years old work obtained an average value of 8798.5<br>U/L, working duration of 10-15 years obtained an average value of 7166.6 U/L, length of work > 15 years obtained<br>an average value of 8264.0 U/L, with a p value (0.396) > 0.05 it can be concluded that there is no effect on the<br>duration of exposure to organophosphate pesticides in the decrease in cholinesterase enzyme activity in the blood of<br>pesticide production operators.</p>}, number={1}, journal={PROCEEDING SURABAYA INTERNATIONAL HEALTH CONFERENCE 2019}, author={Seftiana, Navida and Wulan, Wieke Sri and Wulandari, Devyana Dyah}, year={2020}, month={Jun.}, pages={195–200} }