Case Report Kawasaki Disease
Kawasaki disease is a major cause of heart defects that are often found in children. In Indonesia,
this disease is still rarely diagnosed because it is still considered rare and not yet widely known. The following
two case reports are case reports of boys and girls aged 6 months and 1 year respectively. Both come with
persistent fever for more than four days, rashes on the skin, diarrhea, cracked red lips. Patients with the first
case got red eyes, peeled skin peeled, swollen neck and swollen legs, reddish tongue but not until like
strawberry, the patient was later diagnosed as Kawasaki disease on laboratory examination to get an increase
in C-reactive protein, Blood Sedimentation Rate and Thrombocytosis accompanied by a picture
echocardiography in case 1 was Dilated A. Right coronary and minimal Pericard effusion. Whereas the
second case was accompanied by nausea vomiting, cracked red lips and a strawberry-like tongue, the patient
was later diagnosed as Kawasaki disease on laboratory tests to obtain an increase in C-reactive protein, Blood
Sedimentation Rate and Thrombocytosis with echocardiographic features of TR Light and mild dilatation
RCA . Both children were given intravenous immunoglobulin (IGIV) at a dose of 2 grams / KgBB single dose
and aspirin 25 mg 1x1 while in the case of 2 aspilet a dose of 20 mg 1x1.
Indrarto. 2015. Kawasaki Desease. Berkala Ilmiah Kedokteran Duta Wacana; Vol
(1): 70-78/ISSN : 2460-9684
Lee, K., Rhim, J., and Kang, J. 2012. Kawasaki Disease: Laboratory Findings and an
Immunopathogenesis on the Premise of a “Protein Homeostasis System”. Yonsei Med
J, 53 (2):262-275.
Onouchi, Y., Ozaki, K., Buns, J., Shimizu, C., Hamada, H., Honda, T., Terai, M.
Common variants in CASP3 confer susceptibility to Kawasaki disease, Human
Molecular Genetics, Vol. 19, No. 14 2898–2906, doi:10.1093/hmg/ddq176.
Rowley AH, Shulman ST. Recent advancesin the understanding and management of
Kawasaki disease. Curr Infect Dis Rep.2010;12(2):96–102
Fimbres AM, Shulman T. Kawasaki Desease. Pediatr Rev. 2008:29:308-16
Sundel RP, Petty RE. Kawasaki disease.Dalam: Casidy JT, Petty RE, LaxerRM,
penyunting. Textbook of pediatricrhematology. Edisi ke-5. Philadelphia : Elseiver
Saunders; 2005. hlm. 521–36.
Penyakit Kawasaki (diunduh 1 Juni 2011). Tersedia dari: www.majalah-farmacia.com.
Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, dkk.
Diagnosis, treatment, and long term management of Kawasaki disease: a statement for
health professionals from the committee on rheumatic fever, endocarditis, and
Kawasaki disease, council on cardiovascular disease in the young, American Heart
Association. Pediatrics. 2004;114:1708–33.
Kanegaye JT, Wilder MS, Molkara D, Frazer JR, Pncheri J, Tremoulet AH, dkk.
Recognition of Kawasaki disease shock syndrome. Pediatrics. 2009;123:e783.
American Academy of Pediatrics. Kawasaki syndrome. Dalam: Pickering LK,
penyunting. Red Book: 2003 Report of the Committee on Infectious Diseases. Edisi
ke-26. Elk Grove Village, IL: American Academy of Pediatrics; 2003. hlm. 392–7.
Rowley AH, Shulman ST. Pathogenesis and management of Kawasaki disease. Expert
Rev Anti Infect Ther. 2010;8(2):197–203
AAP Grand Rounds. Is there a role for corticosteroids in treatment of Kawasaki
disease. Elk Grove Village, IL: American Academy of Pediatrics; 2007.
Wooditch AC, Aronoff SC. Effect of initial corticosteroid therapy on coronary artery
aneurisym formation in Kawasaki disease: a meta-analysis of 862 children. Pediatrics.
Marasini M, Pongiglione G, Gazolo D. Late intravenous gammaglobulin treatment in
infants and children with Kawasaki disease and coronary artery abnormalities. Am J
Tizard EJ. Complications of Kawasaki disease. Curr Paed Curr. 2005;15:62-8